Activity Title

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Evolution of TSH Receptor Autoantibody Testing



Autoantibodies to the thyroid stimulating hormone receptor (TSHR) in autoimmune thyroid disease will be discussed.  The focus will be on methods used to test for these autoantibodies.  Bioassays that can assess the functional activity of anti-TSHR will be presented, as will advances in anti-TSHR bioassays.

Intended Audience

This activity is intended for clinical and scientific laboratory professionals, physician - scientists who have an interest in thyroid disease.

Learning Objectives

After completing the activity, the participant should be better able to:

  • Define the importance of autoantibodies to the thyroid stimulating hormone receptor.
  • Differentiate between binding assays and bioassays for anti-TSHR antibodies.
  • Recognize how anti-TSHR bioassays are performed and how they are being improved.

Instruction Level: Advanced


Paul D. Olivo, M.D.,PhD.
Immunologist and Molecular Biologist
Adjunct Assistant Professor
Department of Molecular Microbiology and Microbial Pathogenesis
Washington University Medical School
St. Louis, MO


1.0 hours

Release and Expiration Dates

Release Date: May 10, 2023
Expiration Date: May 10, 2025


The opinions expressed in the educational activity are those of the speaker and do not necessarily represent the views of any organization associated with this activity.

Paul D. Olivo, M.D.,PhD.
- Consultant: Quidel Corporation

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Medium Used

This program has been made available online.

Commercial Support Statement

This activity is provided by the Quidel Corporation.

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